Kishida Lab

Research

<--link to Kenneth T. Kishida's faculty page

Explicit projects statement

(coming soon...)

Vision

Research vision /mission statement

Content coming soon...

Contract with Mentees (mentorship philosophy statement)

Content coming soon...

Diversity Statement

Content coming soon...

Publications

Google Scholar Link

Multi-Task Learning for Sparsity Pattern Heterogeneity: A Discrete Optimization Approach [PDF]

G Loewinger, K Behdin, KT Kishida, G Parmigiani, R Mazumder

arXiv preprint arXiv:2212.08697, 2022

Hierarchical resampling for bagging in multistudy prediction with applications to human neurochemical sensing

G Loewinger, P Patil, KT Kishida, G Parmigiani

The annals of applied statistics 16 (4), 2145-2165, 2022

Computational reinforcement learning, reward (and punishment), and dopamine in psychiatric disorders [PDF]

Brittany Liebenow, Rachel Jones, Emily DiMarco, Jonathan D Trattner, Joseph Humphries, L Paul Sands, Kasey P Spry, Christina K Johnson, Evelyn B Farkas, Angela Jiang, Kenneth T Kishida

Frontiers in Psychiatry 13, 2333, 2022

Intracranial approach for sub-second monitoring of neurotransmitters during DBS electrode implantation does not increase infection rate [PDF]

Brittany Liebenow, Michelle Williams, Thomas Wilson, Ihtsham ul Haq, Mustafa S Siddiqui, Adrian W Laxton, Stephen B Tatter, Kenneth T Kishida

PloS one 17 (8), e0271348, 2022

Subjective Feelings associated with Expectations and Rewards during Risky Decision-making in Impulse Control Disorder [PDF]

Brittany Liebenow, Angela Jiang, Emily DiMarco, Lester Sands, Mary Moya-Mendez, Adrian Laxton, Mustafa Siddiqui, Ihtsham Haq, Kenneth Kishida

2022

Glycemic variability disrupts sleep through KATP channel activity

C Carroll, M Stanley, R Irmen, A Mitra, J Snipes, M Raichle, D Holtzman, R Gould, K Kishida, S Macauley

JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM 42 (1_ SUPPL), 99-100, 2022

P272. Diminished â€˜Punishment Learningâ€™in Patients with Treatment-Resistant Depression [PDF]

Rachel Jones, L Paul Sands, Jonathan D Trattner, Angela Jiang, Heather E Douglas, Predrag V Gligorovic, Kenneth Kishida

Biological Psychiatry 91 (9), S197-S198, 2022

P278. Comorbid Depression and Impulse Control Disorder are Associated With Time Perception Deficits in Parkinsonâ€™s Disease Patients [PDF]

Emily DiMarco, Renata Sadibolova, Rachel Jones, Angela Jiang, Brittany Liebenow, Ihtsham Haq, Mustafa Siddiqui, Devin Terhune, Kenneth Kishida

Biological Psychiatry 91 (9), S200, 2022

Acute hyper-and hypoglycemia uncouples the metabolic cooperation between glucose and lactate to disrupt sleep [PDF]

Caitlin M Carroll, Molly Stanley, Ryan V Raut, Nicholas J Constantino, Riley E Irmen, Anish Mitra, J Andy Snipes, Marcus E Raichle, David M Holtzman, Robert W Gould, Kenneth T Kishida, Shannon L Macauley

bioRxiv, 2022

A Dynamic Affective Core to Bind the Contents, Context, and Value of Conscious Experience [PDF]

Affect Dynamics, 293-328, 2021

Sub-second dopamine and serotonin signaling in human striatum during perceptual decision-making [PDF]

Dan Bang, Kenneth T Kishida, Terry Lohrenz, Jason P White, Adrian W Laxton, Stephen B Tatter, Stephen M Fleming, P Read Montague

Neuron 108 (5), 999-1010. e6, 2020

Role of University of Pennsylvania Smell Identification Test (UPSIT) in diagnosis of Parkinsonian syndromes in a real world setting (1921)

N Pulley, B Liebenow, K Kishida, M Siddiqui

Neurology 94 (15 Supplement), 2020

Diminished single-stimulus response in vmPFC to favorite people in children diagnosed with autism spectrum disorder [PDF]

Kenneth T Kishida, Josepheen De Asis-Cruz, Diane Treadwell-Deering, Brittany Liebenow, Michael S Beauchamp, P Read Montague

Biological psychology 145, 174-184, 2019

COVARIATE-PROFILE SIMILARITY WEIGHTING AND BAGGING STUDIES WITH THE STUDY STRAP: MULTI-STUDY LEARNING FOR HUMAN NEUROCHEMICAL SENSING [PDF]

G Loewinger, P Patil, K Kishida

2019

Random burst sensing of neurotransmitters [PDF]

PR Montague, T Lohrenz, J White, RJ Moran, KT Kishida

bioRxiv, 607077, 2019

The protective action encoding of serotonin transients in the human brain [PDF]

Rosalyn J Moran, Kenneth T Kishida, Terry Lohrenz, Ignacio Saez, Adrian W Laxton, Mark R Witcher, Stephen B Tatter, Thomas L Ellis, Paul EM Phillips, Peter Dayan, P Read Montague

Neuropsychopharmacology 43 (6), 1425-1435, 2018

Computational underpinnings of neuromodulation in humans [PDF]

PR Montague, KT Kishida

Cold Spring Harbor symposia on quantitative biology 83, 71-82, 2018

BOLD and its connection to dopamine release in human striatum: a cross-cohort comparison [PDF]

T Lohrenz, KT Kishida, PR Montague

Philosophical Transactions of the Royal Society B: Biological Sciences 371 â€¦, 2016

An efficiency framework for valence processing systems inspired by soft cross-wiring [PDF]

PR Montague, KT Kishida, RJ Moran, TM Lohrenz

Current opinion in behavioral sciences 11, 121-129, 2016

Subsecond dopamine fluctuations in human striatum encode superposed error signals about actual and counterfactual reward [PDF]

Kenneth T Kishida, Ignacio Saez, Terry Lohrenz, Mark R Witcher, Adrian W Laxton, Stephen B Tatter, Jason P White, Thomas L Ellis, Paul EM Phillips, P Read Montague

Proceedings of the National Academy of Sciences 113 (1), 200-205, 2016

Single-stimulus functional MRI produces a neural individual difference measure for autism spectrum disorder

James T Lu, Kenneth T Kishida, Josepheen De Asis-Cruz, Terry Lohrenz, Diane Treadwell-Deering, Michael Beauchamp, P Read Montague

Clinical Psychological Science 3 (3), 422-432, 2015

Nonpolitical images evoke neural predictors of political ideology [PDF]

Woo-Young Ahn, Kenneth T Kishida, Xiaosi Gu, Terry Lohrenz, Ann Harvey, John R Alford, Kevin B Smith, Gideon Yaffe, John R Hibbing, Peter Dayan, P Read Montague

Current Biology 24 (22), 2693-2699, 2014

Economic probes of mental function and the extraction of computational phenotypes [PDF]

KT Kishida, PR Montague

Journal of Economic Behavior & Organization 94, 234-241, 2013

NEUROBEHAVIORAL INFLUENCE OF CONTROL ON THE EXPRESSION OF INDIVIDUAL DIFFERENCES IN PROBLEM SOLVING CAPACITY

K Kishida, EJ Kim, A Harvey, PR Montague

JOURNAL OF COGNITIVE NEUROSCIENCE, 60-60, 2013

New approaches to investigating social gestures in autism spectrum disorder [PDF]

KT Kishida, J Li, J Schwind, PR Montague

Journal of Neurodevelopmental Disorders 4 (1), 1-11, 2012

Searching for quantitative biomarkers of ASD using computational approaches and rapid assessment fMRI [PDF]

2012

A computational approach to "free wil" constrained by the games we play [PDF]

Frontiers in Integrative Neuroscience 6, 85, 2012

AUTISM SPECTRUM DISORDERS THROUGH A NEUROPHYSIOLOGICAL LENS

MA Patriquin, A Scarpa, BH Friedman, SW White, KT Kishida

PSYCHOPHYSIOLOGY 49, S7-S7, 2012

Imaging models of valuation during social interaction in humans [PDF]

KT Kishida, PR Montague

Biological psychiatry 72 (2), 93-100, 2012

Implicit signals in small group settings and their impact on the expression of cognitive capacity and associated brain responses [PDF]

KT Kishida, D Yang, KH Quartz, SR Quartz, PR Montague

Philosophical Transactions of the Royal Society B: Biological Sciences 367 â€¦, 2012

Sub-second dopamine detection in human striatum [PDF]

Kenneth T Kishida, Stefan G Sandberg, Terry Lohrenz, Youssef G Comair, Ignacio Sáez, Paul EM Phillips, P Read Montague

PloS one 6 (8), e23291, 2011

Neuroeconomic approaches to mental disorders [PDF]

KT Kishida, B King-Casas, PR Montague

Neuron 67 (4), 543-554, 2010

Reactive oxygen species, synaptic plasticity, and memory [PDF]

Oxidative neural injury, 1-27, 2009

Self responses along cingulate cortex reveal quantitative neural phenotype for high-functioning autism [PDF]

Pearl H Chiu, M Amin Kayali, Kenneth T Kishida, Damon Tomlin, Laura G Klinger, Mark R Klinger, P Read Montague

Neuron 57 (3), 463-473, 2008

Sources and targets of reactive oxygen species in synaptic plasticity and memory [PDF]

Antioxidants & redox signaling 9 (2), 233-244, 2007

Synaptic plasticity deficits and mild memory impairments in mouse models of chronic granulomatous disease [PDF]

KT Kishida, CA Hoeffer, D Hu, M Pao, SM Holland, E Klann

Molecular and Cellular Biology 26 (15), 5908-5920, 2006

The Role of NADPH Oxidase in Signal Transduction, Synaptic Plasticity, and Memory in the Hippocampus

Baylor College of Medicine. Department of Neuroscience, 2006

NADPH oxidase is required for NMDA receptorâ€dependent activation of ERK in hippocampal area CA1 [PDF]

KT Kishida, M Pao, SM Holland, E Klann

Journal of neurochemistry 94 (2), 299-306, 2005

Reactive oxygen species: cellular signaling molecules critical for hippocampal LTP and memory

E Klann, F Serrano, MV Tejada-Simon, LE Villasana, KT Kishida

JOURNAL OF NEUROCHEMISTRY 87, 21-21, 2003

Inhibition of baculoviral disease by plant-mediated peroxidase activity and free radical generation [PDF]

Kelli Hoover, Kenneth T Kishida, Louis A DiGiorgio, Jeff Workman, Susan A Alaniz, Bruce D Hammock, Sean S Duffey

Journal of Chemical Ecology 24 (12), 1949-2001, 1998

Modeling Multiple Analytes Using Fast Scan Cyclic Voltammetry

AM Eltahir, JP White, TM Lohrenz, KT Kishida, PR Montague

nan

News

Contact

Looking to volunteer as research study participant or want to learn more about the brain? Are you interested in joining the lab? Use the contact form below or reach out to Dr.K @ kkishida@wakehealth.edu.

Current research studies:

Coming soon...

Statement about research position opportunities:

Coming soon...

LOCATION

One Technology Place
200 E. First Street
Winston-Salem, NC 27101
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Principal Investigator
	Kenneth T. Kishida: Associate Professor » Kenneth T. Kishida is an Associate Professor at Wake Forest School of Medicine with appointments in the Department of Physiology and Pharmacology, the Department of Neurosurgery, and the Department of Biomedical Engineering. His research grapples with the questions of how the human brain gives rise to conscious subjective experiences and how those processes guide human behavior and decision-making.

Lab Technicians
	Angela Jiang: Research Lab Technician » I’ve been a research lab technician in Dr. Kishida’s lab since 2018. I help with collecting behavior, neuroimaging, and voltammetry data. I also program tasks that are used in studies and keep the lab stocked with supplies.
	Ashley R. Shipp: Research Lab Technician » I am a research lab technician... working on cool neuroscience stuff... and also building this website! :)
	Estefanny Villar-Matamoros: Research Lab Technician » Bio coming soon...
	Michael K. Howze: Research Lab Technician » I am a graduate student in Wake’s bioethics program and a research lab tech for the Kishida Lab. I am interested in investigating how social inequities affect brain health and function. Notably, in June 2023, I will matriculate into the anesthesiologist assistant program at VCOM/Bluefield University.
	Zackary A. Whitt: Research Lab Technician » Bio coming soon...

Undergraduate Students
	Hannah S. Yoder: Undergraduate Student » Since joining the lab, I have enjoyed learning how these complex processes can be studied using computational methods and their potential clinical applications. I am excited to continue conducting data analysis as I study how reward prediction errors influence adaptive learning and decision-making, and I hope to build upon my computational studies using neuroimaging.

Graduate Students
	Arian Kolahi Sohrabi: M.D./Ph.D Student » Bio coming soon...
	Bashirul I. Sheikh: Ph.D. Student » I am a first-year Neuroscience PhD student currently rotating with the lab. I am interested in computational models of learning, affect, and decision-making, and studying what goes awry in various clinical presentations.
	Benjamin J. Maas: Ph.D. Student » I am a doctoral biomedical engineering student in the lab with a heavy background in neuroimaging. I'm interested in exploiting computational neuroscience to understand psychiatric disease pathology in the hopes of creating precision medicine for mental health illnesses. Currently, I am researching the neural mechanisms underlying the subjective components of the human experience, specifically affect.
	Emily K. Dimarco: Ph.D. Student » My name is Emily, and I initially joined Wake’s Biomedical Sciences Master’s program before switching over to the Neuroscience program and receiving my Master’s degree. I wrote my Master’s thesis on Millisecond Time Perception in Parkinson’s Disease Patients, and I am interested in better understanding the role that dopamine plays in the cognitive processes associated with the disorder. I am currently pursuing my PhD, with a future interest in attending medical school to continue to study and learn how to treat brain-related illnesses. In my free time, you’ll often find me listening to music or running over at Salem Lake.
	Jonathan D. Trattner: Ph.D. Student » My primary research interests involve human decision-making, specifically neuroeconomics — the synthesis of neuroscience and behavioral economics. I’m also a huge fan of R programming and work on tools for data visualization and statistical modeling.
	Ross Fontana: Ph.D. Student » My interests are in neurochemical measurement techniques and devices. I am working on novel voltammetry technology to improve in vivo neurochemical monitoring for various neurological conditions.
	Rachel E. Jones: Ph.D. Student » I am interested in understanding psychiatric conditions through objective neural measures. My dissertation work utilizes model-based fMRI and reinforcement learning theory to determine how patients with treatment-resistant depression differ in positive and negative valence system-mapped choice behavior, brain activity, and associated subjective feelings. I then determine how electroconvulsive therapy (ECT) changes these model-defined parameters to effectively alleviate depressive symptoms. I hope to eventually predict patient profiles that respond well to ECT.

Postdoctoral Researchers
	Christina K. Johnson: Ph.D. » I am a postdoctoral research fellow, fortunate enough to finish my PhD and join the Kishida Lab just in time for the COVID-19 pandemic. Throughout undergraduate (ASU) and graduate (UMMSoM) school, I was active in hands-on research, ranging from physics and optics to medicine and neurophysiology.

Alumni
	Brittany N. Liebenow: Ph.D. » My research interests join basic neuroscience and its translation to clinical inquiry in neurosurgery and psychiatry. I focus on the novel human voltammetry method of sub-second neurotransmitter measurements, specifically dopamine, during Deep Brain Stimulation electrode implantation neurosurgery.
	Joseph Humphries: M.D. Student » I am interested in the pursuit of the understanding and description of nature which I believe will offer new ways to solve old problems. I see the continued development of conceptual and computational tools in neuroscience as a key development in this process which will one day lead to improvements in the psychological dimension of health care and an improved understanding of ourselves.
	Kasey P. Spry: Ph.D. Student » My name is Kasey and I came to Wake Forest to pursue my interests in neuroscience and neuropsychiatric disorders in the Master’s Neuroscience program. I utilize fast-scan cyclic voltammetry (FSCV), working to better measurements and separation of measurements. This work serves to better clinical studies utilizing FSCV.
	L. Paul Sands III: Ph.D. » Hello, my dissertation research pairs computational modeling of affective human decision-making with within-subject, multi-modal functional human neuroimaging (fMRI and MEG) to study the real-time neurophysiological interactions underlying human choice behavior and subjective feelings. This work leverages fMRI’s high spatial resolution and a model-based analytical design to identify target brain regions for MEG beamforming of event-related neurophysiological activity with millisecond resolution.

	Michelle Marie Williams: Neurosurgery Resident » My interests are primarily neuro-oncological surgery and deep brain stimulation. I am particularly interested in future applications of deep brain stimulation for illnesses that have been traditionally considered psychiatric, such as depression and obsessive-compulsive disorder.

Research

<--link to Kenneth T. Kishida's faculty page

Explicit projects statement

(coming soon...)

Vision

Research vision /mission statement

Content coming soon...

Contract with Mentees (mentorship philosophy statement)

Content coming soon...

Diversity Statement

Content coming soon...

Lab Members / Alumni

Principal Investigator

Kenneth T. Kishida: Associate Professor

Lab Technicians

Angela Jiang: Research Lab Technician

» I’ve been a research lab technician in Dr. Kishida’s lab since 2018. I help with collecting behavior, neuroimaging, and voltammetry data. I also program tasks that are used in studies and keep the lab stocked with supplies.

Ashley R. Shipp: Research Lab Technician

» I am a research lab technician... working on cool neuroscience stuff... and also building this website! :)

Estefanny Villar-Matamoros: Research Lab Technician

» Bio coming soon...

Michael K. Howze: Research Lab Technician

Zackary A. Whitt: Research Lab Technician

» Bio coming soon...

Undergraduate Students

Hannah S. Yoder: Undergraduate Student

Graduate Students

Arian Kolahi Sohrabi: M.D./Ph.D Student

» Bio coming soon...

Bashirul I. Sheikh: Ph.D. Student

» I am a first-year Neuroscience PhD student currently rotating with the lab. I am interested in computational models of learning, affect, and decision-making, and studying what goes awry in various clinical presentations.

Benjamin J. Maas: Ph.D. Student

Emily K. Dimarco: Ph.D. Student

Jonathan D. Trattner: Ph.D. Student

» My primary research interests involve human decision-making, specifically neuroeconomics — the synthesis of neuroscience and behavioral economics. I’m also a huge fan of R programming and work on tools for data visualization and statistical modeling.

Ross Fontana: Ph.D. Student

» My interests are in neurochemical measurement techniques and devices. I am working on novel voltammetry technology to improve in vivo neurochemical monitoring for various neurological conditions.

Rachel E. Jones: Ph.D. Student

Postdoctoral Researchers

Christina K. Johnson: Ph.D.

» I am a postdoctoral research fellow, fortunate enough to finish my PhD and join the Kishida Lab just in time for the COVID-19 pandemic. Throughout undergraduate (ASU) and graduate (UMMSoM) school, I was active in hands-on research, ranging from physics and optics to medicine and neurophysiology.

Alumni

Brittany N. Liebenow: Ph.D.

Joseph Humphries: M.D. Student

Kasey P. Spry: Ph.D. Student

L. Paul Sands III: Ph.D.

Michelle Marie Williams: Neurosurgery Resident

» My interests are primarily neuro-oncological surgery and deep brain stimulation. I am particularly interested in future applications of deep brain stimulation for illnesses that have been traditionally considered psychiatric, such as depression and obsessive-compulsive disorder.

Publications

G Loewinger, K Behdin, KT Kishida, G Parmigiani, R Mazumder

arXiv preprint arXiv:2212.08697, 2022

G Loewinger, P Patil, KT Kishida, G Parmigiani

The annals of applied statistics 16 (4), 2145-2165, 2022

Brittany Liebenow, Rachel Jones, Emily DiMarco, Jonathan D Trattner, Joseph Humphries, L Paul Sands, Kasey P Spry, Christina K Johnson, Evelyn B Farkas, Angela Jiang, Kenneth T Kishida

Frontiers in Psychiatry 13, 2333, 2022

Brittany Liebenow, Michelle Williams, Thomas Wilson, Ihtsham ul Haq, Mustafa S Siddiqui, Adrian W Laxton, Stephen B Tatter, Kenneth T Kishida

PloS one 17 (8), e0271348, 2022

Brittany Liebenow, Angela Jiang, Emily DiMarco, Lester Sands, Mary Moya-Mendez, Adrian Laxton, Mustafa Siddiqui, Ihtsham Haq, Kenneth Kishida

2022

C Carroll, M Stanley, R Irmen, A Mitra, J Snipes, M Raichle, D Holtzman, R Gould, K Kishida, S Macauley

JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM 42 (1_ SUPPL), 99-100, 2022

Rachel Jones, L Paul Sands, Jonathan D Trattner, Angela Jiang, Heather E Douglas, Predrag V Gligorovic, Kenneth Kishida

Biological Psychiatry 91 (9), S197-S198, 2022

Emily DiMarco, Renata Sadibolova, Rachel Jones, Angela Jiang, Brittany Liebenow, Ihtsham Haq, Mustafa Siddiqui, Devin Terhune, Kenneth Kishida

Biological Psychiatry 91 (9), S200, 2022

Caitlin M Carroll, Molly Stanley, Ryan V Raut, Nicholas J Constantino, Riley E Irmen, Anish Mitra, J Andy Snipes, Marcus E Raichle, David M Holtzman, Robert W Gould, Kenneth T Kishida, Shannon L Macauley

bioRxiv, 2022

KT Kishida, LP Sands

Affect Dynamics, 293-328, 2021

Dan Bang, Kenneth T Kishida, Terry Lohrenz, Jason P White, Adrian W Laxton, Stephen B Tatter, Stephen M Fleming, P Read Montague

Neuron 108 (5), 999-1010. e6, 2020

N Pulley, B Liebenow, K Kishida, M Siddiqui

Neurology 94 (15 Supplement), 2020

Kenneth T Kishida, Josepheen De Asis-Cruz, Diane Treadwell-Deering, Brittany Liebenow, Michael S Beauchamp, P Read Montague

Biological psychology 145, 174-184, 2019

G Loewinger, P Patil, K Kishida

2019

PR Montague, T Lohrenz, J White, RJ Moran, KT Kishida

bioRxiv, 607077, 2019

Rosalyn J Moran, Kenneth T Kishida, Terry Lohrenz, Ignacio Saez, Adrian W Laxton, Mark R Witcher, Stephen B Tatter, Thomas L Ellis, Paul EM Phillips, Peter Dayan, P Read Montague